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Research

Publications

Lenz M, Ben Shimon M, Benninger F, Neufeld MY, Shavit-Stein E, Vlachos A, Maggio N: Systemic thrombin-inhibition ameliorates seizures in a mouse model of pilocarpine-induced status epilepticus. Journal of Molecular Medicine 97(3), 1-8; doi: 10.1007/s00109-019-01837-2 (2019).

Reinhardt A, Stichel D, Schrimpf D, Koelsche C, Wefers AK, Ebrahimi A, Sievers P, Huang K, Casalini MB, Fernández-Klett F, Suwala A, Weller M, Gramatzki D, Felsberg J, Reifenberger G, Becker A, Hans VH, Prinz M, Staszewski O, Acker T, Dohmen H, Hartmann C, Paulus W, Heß K, Brokinkel B, Schittenhelm J, Buslei R, Deckert M, Mawrin C, Hewer E, Pohl U, Jaunmuktane Z, Brandner S, Unterberg A, Hänggi D, Platten M, Pfister SM, Wick W, Herold-Mende C, Korshunov A, Reuss DE, Sahm F, Jones DTW, Capper D & von Deimling A: Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities. Acta Neuropathol Commun 7(1), 163; doi: 10.1186/s40478-019-0801-8 (2019).

Nievergelt CM, Maihofer AX, Klengel T, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Dalvie S, Duncan LE, Gelernter J, Levey DF, Logue MW, Polimanti R, Provost AC, Ratanatharathorn A, Stein MB, Torres K, Aiello AE, Almli LM, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegovic E, Babić D, Bækvad-Hansen M, Baker DG, Beckham JC, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Børglum AD, Bradley B, Brashear M, Breen G, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Calabrese JR, Caldas-de-Almeida JM, Dale AM, Daly MJ, Daskalakis NP, Deckert J, Delahanty DL, Dennis MF, Disner SG, Domschke K, Dzubur-Kulenovic A, Erbes CR, Evans A, Farrer LA, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Geuze E, Gillespie C, Uka AG, Gordon SD, Guffanti G, Hammamieh R, Harnal S, Hauser MA, Heath AC, Hemmings SMJ, Hougaard DM, Jakovljevic M, Jett M, Johnson EO, Jones I, Jovanovic T, Qin XJ, Junglen AG, Karstoft KI, Kaufman ML, Kessler RC, Khan A, Kimbrel NA, King AP, Koen N, Kranzler HR, Kremen WS, Lawford BR, Lebois LAM, Lewis CE, Linnstaedt SD, Lori A, Lugonja B, Luykx JJ, Lyons MJ, Maples-Keller J, Marmar C, Martin AR, Martin NG, Maurer D, Mavissakalian MR, McFarlane A, McGlinchey RE, McLaughlin KA, McLean SA, McLeay S, Mehta D, Milberg WP, Miller MW, Morey RA, Morris CP, Mors O, Mortensen PB, Neale BM, Nelson EC, Nordentoft M, Norman SB, O’Donnell M, Orcutt HK, Panizzon MS, Peters ES, Peterson AL, Peverill M, Pietrzak RH, Polusny MA, Rice JP, Ripke S, Risbrough VB, Roberts AL, Rothbaum AO, Rothbaum BO, Roy-Byrne P, Ruggiero K, Rung A, Rutten BPF, Saccone NL, Sanchez SE, Schijven D, Seedat S, Seligowski AV, Seng JS, Sheerin CM, Silove D, Smith AK, Smoller JW, Sponheim SR, Stein DJ, Stevens JS, Sumner JA, Teicher MH, Thompson WK, Trapido E, Uddin M, Ursano RJ, van den Heuvel LL, Van Hooff M, Vermetten E, Vinkers CH, Voisey J, Wang Y, Wang Z, Werge T, Williams MA, Williamson DE, Winternitz S, Wolf C, Wolf EJ, Wolff JD, Yehuda R, Young RM, Young KA, Zhao H, Zoellner LA, Liberzon I, Ressler KJ, Haas M, Koenen KC: International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nat Commun 10(1), 4558; doi: 10.1038/s41467-019-12576-w (2019).

Prinz M, Jung S, Priller J: Microglia Biology: One Century of Evolving Concepts. Cell 179(2), 292-311; doi: 10.1016/j.cell.2019.08.053 (2019).

Kierdorf K, Prinz M: Microglia: Same same, but different. J Exp Med 216(10), 2223-2225; doi: 10.1084/jem.20191535 (2019).

O’Connor T, Zhou X, Kosla J, Adili A, Garcia Beccaria M, Kotsiliti E, Pfister D, Johlke AL, Sinha A, Sankowski R, Schick M, Lewis R, Dokalis N, Seubert B, Höchst B, Inverso D, Heide D, Zhang W, Weihrich P, Manske K, Wohlleber D, Anton M, Hoellein A, Seleznik G, Bremer J, Bleul S, Augustin HG, Scherer F, Koedel U, Weber A, Protzer U, Förster R, Wirth T, Aguzzi A, Meissner F, Prinz M, Baumann B, Höpken UE, Knolle PA, von Baumgarten L, Keller U, Heikenwalder M: Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. Cancer Cell 36(3), 250-267.e9; doi: 10.1016/j.ccell.2019.08.001 (2019).

Büttner C, Heer M, Traichel J, Schwemmle M & Heimrich B: Zika Virus-Mediated Death of Hippocampal Neurons Is Independent From Maturation State. Front Cell Neurosci 13, 389; doi: 10.3389/fncel.2019.00389 (2019).

Kneer K, Reinhard J, Ziegler C, Slyschak A, Schiele M, Vietz M, Peters K, Meisenzahl EM, Pauli P, Reif A, Deckert J, Romanos M, Domschke K, Neufang S: Serotonergic influence on depressive symptoms and trait anxiety is mediated by negative life events and frontal activation in children and adolescents. Eur Child Adolesc Psychiatry; doi: 10.1007/s00787-019-01389-3 (2019).

Lenz M & Vlachos A: The neuroimmunological synapse: from synaptic homeostasis to brain disease. Neuroforum 25(3); doi:10.1515/nf-2019-0 (2019).

Böttcher C, Sankowski R, Priller J, Prinz M: CNS myeloid cell heterogeneity at the single-cell level. Neuroforum 25(3); doi:10.1515/nf-2018-0034 (2019).

Kierdorf K, Masuda T, Jordão MJC, Prinz M: Macrophages at CNS interfaces: ontogeny and function in health and disease. Nat Rev Neurosci 20(9), 547-562; doi: 10.1038/s41583-019-0201-x (2019).

Schiele MA, Kollert L, Lesch K-P, Arolt V, Zwanzger P, Deckert J, Ziegler C, Domschke K: Hypermethylation of the serotonin transporter gene promoter in panic disorder-Epigenetic imprint of comorbid depression? Eur Neuropsychopharmacol 29(10), 1161-1167; doi: 10.1016/j.euroneuro.2019.07.131 (2019).

Priller J, Prinz M: Targeting microglia in brain disorders. Science 365(6448), 32-33; doi: 10.1126/science.aau9100 (2019).

Schwabenland M, Mossad O, Peres AG, Kessler F, Mocayar Maron FJ, Harsan L-A, Bienert T, von Elverfeldt D, Knobeloch K-P, Staszewski O, Heppner FL, Meuwissen MEC, Mancini GMS, Prinz M & Blank T: Loss of USP18 in microglia induces white matter pathology. Acta Neuropathol Commun 7(1), 106; doi: 10.1186/s40478-019-0757-8 (2019).

Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O’Connor T, Weston CJ, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M: Platelet GPIba is a mediator and potential interventional target for NASH and subsequent liver cancer. Nat Med 25(4), 641-655; doi: 10.1038/s41591-019-0379-5 (2019).

Henrik Heiland D, Ravi VM, Behringer SP, Frenking JH, Wurm J, Joseph K, Garrelfs NWC, Strähle J, Heynckes S, Grauvogel J, Franco P, Mader I, Schneider M, Potthoff AL, Delev D, Hofmann UG, Fung C, Beck J, Sankowski R, Prinz M, Schnell O: Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma. Nat Commun 10(1), 2541; doi: 10.1038/s41467-019-10493-6 (2019).