Call us +49 (0) 761 / 270-51190

Research

Publications

Cook J and Prinz M: Regulation of microglial physiology by the microbiota. Gut Microbes 14(1):2125739, doi: 10.1080/19490976.2022.2125739 (2022).

Aktories P, Petry P, Glatz P, Andrieux G, Oschwald A, Botterer H, Gorka O, Erny D, Boerries M, Henneke P, Groß O, Prinz M, Kierdorf K: An improved organotypic cell culture system to study tissue-resident macrophages ex vivo. Cell Reports Methods, 2(8), 100260, https://doi.org/10.1016/j.crmeth.2022.100260 (2022).

Reinhardt A, Pfister K, Schrimpf D, Stichel D, Sahm F, Reuss DE, Capper D, Wefers AK, Ebrahimi A, Sill M, Felsberg J, Reifenberger G, Becker A, Prinz M, […] von Deimling A: Anaplastic ganglioglioma – A diagnosis comprising several distinct tumour types. Neuropathol Appl Neurobiol e12847, doi: 10.1111/nan.12847 (2022).

Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Reddy Bandi S, Arampatzi P, Krammer T, DiFabion N, Dietrich OArias-Loza AP, Prinz M, Mack M, Schlepckow K, Haass C, Silvestre JS, Zernecke A, Saliba AE, Cochain C: Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction. Cardiovasc Res, cvac113, https://doi.org/10.1093/cvr/cvac113 (2022).

Ziegler-Waldkirch S, Friesen M, Loreth D, Sauer J-F, Kemna S, Hilse A, Erny D, Helm C, d´Errico P, Prinz M, Bartos M & Meyer-Luehmann M: Seed-induced Aβ deposition alters neuronal function and impairs olfaction in a mouse model of Alzheimer’s disease. Mol Psychiatry, doi: 10.1038/s41380-022-01686-5 (2022).

Jiao H, Wachsmuth L, Wolf S, Lohmann J, Nagata M, Gökberk Kaya G, Oikonomou N, Kondylis V, Rogg M, Diebold M, Tröder SE, Zevnik B, Prinz M, Schell C, Young GR, Kassiotis G & Pasparakis M: ADAR1 averts fatal type I interferon induction by ZBP1. Nature  607,  776–783 (2022).

Ravi VM, Will P, Kueckelhaus J, Sun N, Joseph K, Salié H, . . . Prinz M, . . .Heiland DH: Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma. Cancer Cell, 40(6), 639-655.e613 (2022).

Friedrich M, Hahn M, Michel J, Sankowski R, Kilian M, Kehl N, . . . Prinz M, . . . Bunse L: Dysfunctional dendritic cells limit antigen-specific T cell response in glioma. Neuro-Oncology. https://doi.org/10.1093/neuonc/noac138 (2022).

Kolter J, Henneke P, Groß O, Kierdorf K, Prinz M, Graf L & Schwemmle M: Paradoxical immunodeficiencies – When failures of innate immunity cause immunopathology. European Journal of Immunology https://doi.org/10.1002/eji.202149531 (2022).

Boettler T, Csernalabics B, Salié H, Luxenburger H, Wischer L, Salimi Alizei E, Zoldan K, Krimmel L, Bronsert P, Schwabenland M, Prinz M, Mogler C, Neumann-Haefelin C, Thimme R, Hofmann M, and Bengsch B: SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis. J Hepatol; doi: 10.1016/j.jhep.2022.03.040 (2022).

Steinkellner H, Kempaiah P, Beribisky AV, Pferschy S, Etzler J, Huber A, Sarne V, Neuhaus W, Kuttke M, Bauer J, Arunachalam JP, Christodoulou J, Dressel R, Mildner A, Prinz M, Laccone F: TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome. Int J Biol Macromol 209(Pt A):972-983; doi: 10.1016/j.ijbiomac.2022.04.080 2022).

Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernández-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lämmermann T, Priller J, Kierdorf K, Prinz M: Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature 604(7907):740-748; doi: 10.1038/s41586-022-04596-2 (2022).

Matsudaira T & Prinz M: Life and death of microglia: Mechanisms governing microglial states and fates. Immunol Lett 245:51-60; doi: 10.1016/j.imlet.2022.04.001 (2022).

Yogev N, Bedke T, Kobayashi Y, Brockmann L, Lukas D, Regen T, Croxford AL, Nikolav A, Hövelmeyer N, von Stebut E, Prinz M, Ubeda C, Maloy KJ, Gagliani N, Flavell RA, Waisman A, Huber S: CD4 + T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survival. Cell Rep 38(13):110565; doi: 10.1016/j.celrep.2022.110565 (2022).

Erny D, Dokalis N, Mezö C, Mossad O, Blank T, Prinz M: Flow-cytometry-based protocol to analyze respiratory chain function in mouse microglia. STAR Protoc 3(1):101186; doi: 10.1016/j.xpro.2022.101186 (2022).

Conforti P, Mezey S, Nath S, Chu Y-H, Malik SC, Martínez Santamaría JC, Deshpande SS, Pous L, Zieger B, Schachtrup C: Fibrinogen regulates lesion border-forming reactive astrocyte properties after vascular damage. Glia, doi: 10.1002/glia.24166 (2022).