Call us +49 (0) 761 / 270-51190

Research

Publications

Ravi VM, Will P, Kueckelhaus J, Sun N, Joseph K, Salié H, . . . Prinz M, . . .Heiland DH: Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma. Cancer Cell, 40(6), 639-655.e613 (2022).

Friedrich M, Hahn M, Michel J, Sankowski R, Kilian M, Kehl N, . . . Prinz M, . . . Bunse L: Dysfunctional dendritic cells limit antigen-specific T cell response in glioma. Neuro-Oncology. https://doi.org/10.1093/neuonc/noac138 (2022).

Kolter J, Henneke P, Groß O, Kierdorf K, Prinz M, Graf L & Schwemmle M: Paradoxical immunodeficiencies – When failures of innate immunity cause immunopathology. European Journal of Immunology https://doi.org/10.1002/eji.202149531 (2022).

Boettler T, Csernalabics B, Salié H, Luxenburger H, Wischer L, Salimi Alizei E, Zoldan K, Krimmel L, Bronsert P, Schwabenland M, Prinz M, Mogler C, Neumann-Haefelin C, Thimme R, Hofmann M, and Bengsch B: SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis. J Hepatol; doi: 10.1016/j.jhep.2022.03.040 (2022).

Steinkellner H, Kempaiah P, Beribisky AV, Pferschy S, Etzler J, Huber A, Sarne V, Neuhaus W, Kuttke M, Bauer J, Arunachalam JP, Christodoulou J, Dressel R, Mildner A, Prinz M, Laccone F: TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome. Int J Biol Macromol 209(Pt A):972-983; doi: 10.1016/j.ijbiomac.2022.04.080 2022).

Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernández-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lämmermann T, Priller J, Kierdorf K, Prinz M: Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature 604(7907):740-748; doi: 10.1038/s41586-022-04596-2 (2022).

Matsudaira T & Prinz M: Life and death of microglia: Mechanisms governing microglial states and fates. Immunol Lett 245:51-60; doi: 10.1016/j.imlet.2022.04.001 (2022).

Yogev N, Bedke T, Kobayashi Y, Brockmann L, Lukas D, Regen T, Croxford AL, Nikolav A, Hövelmeyer N, von Stebut E, Prinz M, Ubeda C, Maloy KJ, Gagliani N, Flavell RA, Waisman A, Huber S: CD4 + T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survival. Cell Rep 38(13):110565; doi: 10.1016/j.celrep.2022.110565 (2022).

Erny D, Dokalis N, Mezö C, Mossad O, Blank T, Prinz M: Flow-cytometry-based protocol to analyze respiratory chain function in mouse microglia. STAR Protoc 3(1):101186; doi: 10.1016/j.xpro.2022.101186 (2022).

Conforti P, Mezey S, Nath S, Chu Y-H, Malik SC, Martínez Santamaría JC, Deshpande SS, Pous L, Zieger B, Schachtrup C: Fibrinogen regulates lesion border-forming reactive astrocyte properties after vascular damage. Glia, doi: 10.1002/glia.24166 (2022).

Schachtrup C: Modulating scar formation for improving brain repair: from coagulation and inflammation to cell therapy. Cell Tissue Res, doi: 10.1007/s00441-022-03601-4 (2022).

Dudek M, Lohr K, Donakonda S, Baumann T, Lüdemann M, Hegenbarth S, Dübbel L, Eberhagen C, Michailidou S, Yassin A, Prinz M, Popper B, Rose-John S, Zischka H, Knolle PA: IL-6-induced FOXO1 activity determines the dynamics of metabolism in CD8 T cells cross-primed by liver sinusoidal endothelial cells. Cell Rep 38(7):110389; doi: 10.1016/j.celrep.2022.110389 (2022).

Czeh M, Stäble S, Krämer S, Tepe L, Talyan S, Carrelha J, Meng Y, Heitplatz B, Schwabenland M, Milsom MD, Plass C, Prinz M, Schlesner M, Andrade-Navarro MA, Nerlov C, Jacobsen SEW, Lipka DB, Rosenbauer F: DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease. J Immunol 208(2), 358-370 (2022).

Kleis P, Paschen E, Häussler U, Bernal Sierra YA, Haas CA: Long-term in vivo characterization and application of a novel potassium channel-based optogenetic silencer in the healthy and epileptic mouse hippocampus. BMC Biology 20, 18 (2022).

Ebrahimi A, Korshunov A, Reifenberger G, Capper D, Felsberg J, Trisolini E, Pollo B, Calatozzolo C, Prinz M, Staszewski O, Schweizer L, Schittenhelm J, Harter PN, Paulus W, Thomas C, Kohlhof‑Meinecke P, Seiz‑Rosenhagen M, Milde T, Casalini BM, Suwala A, Wefers AK, Reinhardt A, Sievers P, Kramm CM, Etminam N, Unterberg A, Wick W, Herold‑Mende C, Sturm D, Pfister SM, Sill M, Jones DTW, Schrimpf D, Reuss DE, Aldape K, Abdullaev Z, Sahm F, von Deimling A and Stichel D: Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival. Acta Neuropathol Commun 10(1):5 (2022).