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Research

Publications

Schwabenland M, Mossad O, Peres AG, Kessler F, Mocayar Maron FJ, Harsan L-A, Bienert T, von Elverfeldt D, Knobeloch K-P, Staszewski O, Heppner FL, Meuwissen MEC, Mancini GMS, Prinz M & Blank T: Loss of USP18 in microglia induces white matter pathology. Acta Neuropathol Commun 7(1), 106; doi: 10.1186/s40478-019-0757-8 (2019).

Henrik Heiland D, Ravi VM, Behringer SP, Frenking JH, Wurm J, Joseph K, Garrelfs NWC, Strähle J, Heynckes S, Grauvogel J, Franco P, Mader I, Schneider M, Potthoff AL, Delev D, Hofmann UG, Fung C, Beck J, Sankowski R, Prinz M, Schnell O: Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma. Nat Commun 10(1), 2541; doi: 10.1038/s41467-019-10493-6 (2019).

Fischer J, Walter C, Tönges A, Aleth H, Jordão MJC, Leddin M, Gröning V, Erdmann T, Lenz G, Roth J, Vogl T, Prinz M, Dugas M, Jacobsen ID, Rosenbauer F: Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils. Nat Immunol 20(5), 546-558; doi: 10.1038/s41590-019-0343-z (2019).

Masuda T, Sankowski R, Staszewski O, Böttcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grün D, Priller J, Stadelmann C, Prinz M: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature 566(7744), 388-392; doi: 10.1038/s41586-019-0924-x (2019).

Howard DM, Adams MJ, Clarke T-K, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA, 23andMe Research Team, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski M, Byrne EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM & McIntosh AM: Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. Nat Neurosci 22(3), 343-352; doi: 10.1038/s41593-018-0326-7 (2019).

Gottschalk MG, Richter J, Ziegler C, Schiele MA, Mann J, Geiger MJ, Schartner C, Homola GA, Alpers GW, Büchel C, Fehm L, Fydrich T, Gerlach AL, Gloster AT, Helbig-Lang S, Kalisch R, Kircher T, Lang T, Lonsdorf TB, Pané-Farré CA, Ströhle A, Weber H, Zwanzger P, Arolt V, Romanos M, Wittchen HU, Hamm A, Pauli P, Reif A, Deckert J, Neufang S, Höfler M, Domschke K: Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes. Transl Psychiatry 9(1), 75; doi: 10.1038/s41398-019-0415-8 (2019).

Schiele MA, Herzog K, Kollert L, Böhnlein J, Repple J, Rosenkranz K, Leehr EJ, Ziegler C, Lüken U, Dannlowski U, Pauli P, Arolt V, Zwanzger P, Deckert J, Erfurth A, Domschke K: Affective temperaments (TEMPS-A) in panic disorder and healthy probands – genetic modulation by 5-HTT variation. World J Biol Psychiatry; doi: 10.1080/15622975.2019.1705999 (in print, 2020).

Jordão MJC, Sankowski R, Brendecke SM, Sagar, Locatelli G, Tai YH, Tay TL, Schramm E, Armbruster S, Hagemeyer N, Groß O, Mai D, Çiçek Ö, Falk T, Kerschensteiner M, Grün D, Prinz M: Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation. Science 363(6425); pii: eaat7554; doi: 10.1126/science.aat7554 (2019).